BDBM50168195 4-[2-(4-Fluoro-phenyl)-5-(1-methyl-piperidin-4-yl)-1H-pyrrol-3-yl]-2-methyl-pyridine::CHEMBL371842

SMILES: CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(C)c1

InChI Key: InChIKey=AUOITMPSLFBTFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50168195 (4-[2-(4-Fluoro-phenyl)-5-(1-methyl-piperidin-4-yl)...) Show SMILES CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(C)c1 Show InChI InChI=1S/C22H24FN3/c1-15-13-18(7-10-24-15)20-14-21(16-8-11-26(2)12-9-16)25-22(20)17-3-5-19(23)6-4-17/h3-7,10,13-14,16,25H,8-9,11-12H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase				Bioorg Med Chem Lett 15: 3296-301 (2005) Article DOI: 10.1016/j.bmcl.2005.04.060 BindingDB Entry DOI: 10.7270/Q24M9421
					More data for this Ligand-Target Pair