US11028058, Compound 1.304

SMILES: Cn1ccc(n1)-c1nc(N)cnc1-c1cc(Cl)c2[nH]ncc2c1

InChI Key: InChIKey=CQVKACDCKIDJPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM501682 (US11028058, Compound 1.304) Show SMILES Cn1ccc(n1)-c1nc(N)cnc1-c1cc(Cl)c2[nH]ncc2c1 Show InChI InChI=1S/C15H12ClN7/c1-23-3-2-11(22-23)15-14(18-7-12(17)20-15)8-4-9-6-19-21-13(9)10(16)5-8/h2-7H,1H3,(H2,17,20)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
NUVATION BIO INC. US Patent					Assay Description For the A2A adenosine receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ...				US Patent US11028058 (2021)
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