BDBM50169579 2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid bis-cyclopropylmethyl-amide::CHEMBL178165

SMILES: CCc1nc2N(CCn2c1C(=O)N(CC1CC1)CC1CC1)c1c(C)cc(C)cc1C

InChI Key: InChIKey=XQQUWBOTKMKOPS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50169579 (2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-...) Show SMILES CCc1nc2N(CCn2c1C(=O)N(CC1CC1)CC1CC1)c1c(C)cc(C)cc1C Show InChI InChI=1S/C25H34N4O/c1-5-21-23(24(30)27(14-19-6-7-19)15-20-8-9-20)29-11-10-28(25(29)26-21)22-17(3)12-16(2)13-18(22)4/h12-13,19-20H,5-11,14-15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr-o- CRF from human corticotropin releasing factor receptor 1 expressed in IMR-32 cells				Bioorg Med Chem Lett 15: 3870-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.117 BindingDB Entry DOI: 10.7270/Q269733T
					More data for this Ligand-Target Pair