BDBM50169592 2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid (2-cyclopropyl-ethyl)-ethyl-amide::CHEMBL181287

SMILES: CCN(CCC1CC1)C(=O)c1c(CC)nc2N(CCn12)c1c(C)cc(C)cc1C

InChI Key: InChIKey=ZCRGIWQCPZUCIE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50169592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50169592 (2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-...) Show SMILES CCN(CCC1CC1)C(=O)c1c(CC)nc2N(CCn12)c1c(C)cc(C)cc1C Show InChI InChI=1S/C24H34N4O/c1-6-20-22(23(29)26(7-2)11-10-19-8-9-19)28-13-12-27(24(28)25-20)21-17(4)14-16(3)15-18(21)5/h14-15,19H,6-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr-o- CRF from human corticotropin releasing factor receptor 1 expressed in IMR-32 cells				Bioorg Med Chem Lett 15: 3870-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.117 BindingDB Entry DOI: 10.7270/Q269733T
					More data for this Ligand-Target Pair