BDBM50169629 9-Cyclobutyl-2-(2-ethoxy-phenyl)-1,9-dihydro-purin-6-one::CHEMBL361136
SMILES: CCOc1ccccc1-c1nc2n(cnc2c(=O)[nH]1)C1CCC1
InChI Key: InChIKey=DXOFVCUNIQMKDW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50169629 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphodiesterase 1
(Homo sapiens (Human)) | BDBM50169629
(9-Cyclobutyl-2-(2-ethoxy-phenyl)-1,9-dihydro-purin...)Show InChI InChI=1S/C17H18N4O2/c1-2-23-13-9-4-3-8-12(13)15-19-16-14(17(22)20-15)18-10-21(16)11-6-5-7-11/h3-4,8-11H,2,5-7H2,1H3,(H,19,20,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER HealthCare AG
Curated by ChEMBL
| Assay Description
Inhibition of phosphodiesterase 1 |
Bioorg Med Chem Lett 15: 3900-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.090
BindingDB Entry DOI: 10.7270/Q2XS5TWD |
More data for this
Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human)) | BDBM50169629
(9-Cyclobutyl-2-(2-ethoxy-phenyl)-1,9-dihydro-purin...)Show InChI InChI=1S/C17H18N4O2/c1-2-23-13-9-4-3-8-12(13)15-19-16-14(17(22)20-15)18-10-21(16)11-6-5-7-11/h3-4,8-11H,2,5-7H2,1H3,(H,19,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER HealthCare AG
Curated by ChEMBL
| Assay Description
Inhibition of phosphodiesterase 5 |
Bioorg Med Chem Lett 15: 3900-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.090
BindingDB Entry DOI: 10.7270/Q2XS5TWD |
More data for this
Ligand-Target Pair | |
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