BDBM50169642 9-Cyclopropyl-2-(2-ethoxy-phenyl)-1,9-dihydro-purin-6-one::CHEMBL360508

SMILES: CCOc1ccccc1-c1nc2n(cnc2c(=O)[nH]1)C1CC1

InChI Key: InChIKey=JLVYUNCWJCTICJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50169642 (9-Cyclopropyl-2-(2-ethoxy-phenyl)-1,9-dihydro-puri...) Show SMILES CCOc1ccccc1-c1nc2n(cnc2c(=O)[nH]1)C1CC1 Show InChI InChI=1S/C16H16N4O2/c1-2-22-12-6-4-3-5-11(12)14-18-15-13(16(21)19-14)17-9-20(15)10-7-8-10/h3-6,9-10H,2,7-8H2,1H3,(H,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5				Bioorg Med Chem Lett 15: 3900-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.090 BindingDB Entry DOI: 10.7270/Q2XS5TWD
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50169642 (9-Cyclopropyl-2-(2-ethoxy-phenyl)-1,9-dihydro-puri...) Show SMILES CCOc1ccccc1-c1nc2n(cnc2c(=O)[nH]1)C1CC1 Show InChI InChI=1S/C16H16N4O2/c1-2-22-12-6-4-3-5-11(12)14-18-15-13(16(21)19-14)17-9-20(15)10-7-8-10/h3-6,9-10H,2,7-8H2,1H3,(H,18,19,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 1				Bioorg Med Chem Lett 15: 3900-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.090 BindingDB Entry DOI: 10.7270/Q2XS5TWD
					More data for this Ligand-Target Pair