BDBM50169644 3-Cyclopentyl-5-(2-ethoxy-phenyl)-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one::CHEMBL361864

SMILES: CCOc1ccccc1-c1nc2n(nnc2c(=O)[nH]1)C1CCCC1

InChI Key: InChIKey=DDKCZVDGSHWYON-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50169644 (3-Cyclopentyl-5-(2-ethoxy-phenyl)-3,6-dihydro-[1,2...) Show SMILES CCOc1ccccc1-c1nc2n(nnc2c(=O)[nH]1)C1CCCC1 Show InChI InChI=1S/C17H19N5O2/c1-2-24-13-10-6-5-9-12(13)15-18-16-14(17(23)19-15)20-21-22(16)11-7-3-4-8-11/h5-6,9-11H,2-4,7-8H2,1H3,(H,18,19,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5				Bioorg Med Chem Lett 15: 3900-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.090 BindingDB Entry DOI: 10.7270/Q2XS5TWD
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50169644 (3-Cyclopentyl-5-(2-ethoxy-phenyl)-3,6-dihydro-[1,2...) Show SMILES CCOc1ccccc1-c1nc2n(nnc2c(=O)[nH]1)C1CCCC1 Show InChI InChI=1S/C17H19N5O2/c1-2-24-13-10-6-5-9-12(13)15-18-16-14(17(23)19-15)20-21-22(16)11-7-3-4-8-11/h5-6,9-11H,2-4,7-8H2,1H3,(H,18,19,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
BAYER HealthCare AG Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 1				Bioorg Med Chem Lett 15: 3900-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.090 BindingDB Entry DOI: 10.7270/Q2XS5TWD
					More data for this Ligand-Target Pair