BDBM50169654 5-(2,6-Dimethyl-hept-5-enyl)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL360016

SMILES: [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-c1scnc1-[#6](=O)-[#7]-c1nccs1

InChI Key: InChIKey=HXXGGECLJBMMNB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169654 (5-(2,6-Dimethyl-hept-5-enyl)-thiazole-4-carboxylic...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-c1scnc1-[#6](=O)-[#7]-c1nccs1 Show InChI InChI=1S/C16H21N3OS2/c1-11(2)5-4-6-12(3)9-13-14(18-10-22-13)15(20)19-16-17-7-8-21-16/h5,7-8,10,12H,4,6,9H2,1-3H3,(H,17,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169654 (5-(2,6-Dimethyl-hept-5-enyl)-thiazole-4-carboxylic...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-c1scnc1-[#6](=O)-[#7]-c1nccs1 Show InChI InChI=1S/C16H21N3OS2/c1-11(2)5-4-6-12(3)9-13-14(18-10-22-13)15(20)19-16-17-7-8-21-16/h5,7-8,10,12H,4,6,9H2,1-3H3,(H,17,19,20)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair