BDBM50169655 5-(2-Piperidin-1-yl-acetylamino)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL369255

SMILES: O=C(CN1CCCCC1)Nc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=YSDROGRUJBHEBM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169655 (5-(2-Piperidin-1-yl-acetylamino)-thiazole-4-carbox...) Show SMILES O=C(CN1CCCCC1)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H17N5O2S2/c20-10(8-19-5-2-1-3-6-19)17-13-11(16-9-23-13)12(21)18-14-15-4-7-22-14/h4,7,9H,1-3,5-6,8H2,(H,17,20)(H,15,18,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169655 (5-(2-Piperidin-1-yl-acetylamino)-thiazole-4-carbox...) Show SMILES O=C(CN1CCCCC1)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H17N5O2S2/c20-10(8-19-5-2-1-3-6-19)17-13-11(16-9-23-13)12(21)18-14-15-4-7-22-14/h4,7,9H,1-3,5-6,8H2,(H,17,20)(H,15,18,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair