BDBM50169659 CHEMBL362868::[4-(Thiazol-2-ylcarbamoyl)-thiazol-5-yl]-carbamic acid

SMILES: OC(=O)Nc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=ZZGKLPKDNIJXQP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169659 (CHEMBL362868 | [4-(Thiazol-2-ylcarbamoyl)-thiazol-...) Show SMILES OC(=O)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C8H6N4O3S2/c13-5(11-7-9-1-2-16-7)4-6(12-8(14)15)17-3-10-4/h1-3,12H,(H,14,15)(H,9,11,13)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169659 (CHEMBL362868 | [4-(Thiazol-2-ylcarbamoyl)-thiazol-...) Show SMILES OC(=O)Nc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C8H6N4O3S2/c13-5(11-7-9-1-2-16-7)4-6(12-8(14)15)17-3-10-4/h1-3,12H,(H,14,15)(H,9,11,13)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair