null

SMILES: O=C(Nc1nccs1)c1cscn1

InChI Key: InChIKey=HAODSJCJLHAVEW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169662 (CHEMBL175540 | Thiazole-4-carboxylic acid thiazol-...) Show SMILES O=C(Nc1nccs1)c1cscn1 Show InChI InChI=1S/C7H5N3OS2/c11-6(5-3-12-4-9-5)10-7-8-1-2-13-7/h1-4H,(H,8,10,11)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against ScMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair
Methionine aminopeptidase (Escherichia coli (strain K12))	BDBM50169662 (CHEMBL175540 | Thiazole-4-carboxylic acid thiazol-...) Show SMILES O=C(Nc1nccs1)c1cscn1 Show InChI InChI=1S/C7H5N3OS2/c11-6(5-3-12-4-9-5)10-7-8-1-2-13-7/h1-4H,(H,8,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169662 (CHEMBL175540 | Thiazole-4-carboxylic acid thiazol-...) Show SMILES O=C(Nc1nccs1)c1cscn1 Show InChI InChI=1S/C7H5N3OS2/c11-6(5-3-12-4-9-5)10-7-8-1-2-13-7/h1-4H,(H,8,10,11)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine aminopeptidase (Escherichia coli (strain K12))	BDBM50169662 (CHEMBL175540 | Thiazole-4-carboxylic acid thiazol-...) Show SMILES O=C(Nc1nccs1)c1cscn1 Show InChI InChI=1S/C7H5N3OS2/c11-6(5-3-12-4-9-5)10-7-8-1-2-13-7/h1-4H,(H,8,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against EcMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair