BDBM50169664 5-(2-Methoxy-propyl)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL178091

SMILES: COC(C)Cc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=KZEVEDBAQBDXNN-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169664 (5-(2-Methoxy-propyl)-thiazole-4-carboxylic acid th...) Show SMILES COC(C)Cc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C11H13N3O2S2/c1-7(16-2)5-8-9(13-6-18-8)10(15)14-11-12-3-4-17-11/h3-4,6-7H,5H2,1-2H3,(H,12,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against EcMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169664 (5-(2-Methoxy-propyl)-thiazole-4-carboxylic acid th...) Show SMILES COC(C)Cc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C11H13N3O2S2/c1-7(16-2)5-8-9(13-6-18-8)10(15)14-11-12-3-4-17-11/h3-4,6-7H,5H2,1-2H3,(H,12,14,15)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169664 (5-(2-Methoxy-propyl)-thiazole-4-carboxylic acid th...) Show SMILES COC(C)Cc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C11H13N3O2S2/c1-7(16-2)5-8-9(13-6-18-8)10(15)14-11-12-3-4-17-11/h3-4,6-7H,5H2,1-2H3,(H,12,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169664 (5-(2-Methoxy-propyl)-thiazole-4-carboxylic acid th...) Show SMILES COC(C)Cc1scnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C11H13N3O2S2/c1-7(16-2)5-8-9(13-6-18-8)10(15)14-11-12-3-4-17-11/h3-4,6-7H,5H2,1-2H3,(H,12,14,15)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against ScMetAP1 enzyme activity				Bioorg Med Chem Lett 15: 4130-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.005 BindingDB Entry DOI: 10.7270/Q2FN15RH
					More data for this Ligand-Target Pair