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SMILES: OC(=O)CC(=O)Nc1scnc1C(=O)Nc1nccs1

InChI Key: InChIKey=OYPJZAIDSYWSEE-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169681   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)
BDBM50169681
PNG
(CHEMBL178736 | N-[4-(Thiazol-2-ylcarbamoyl)-thiazo...)
Show SMILES OC(=O)CC(=O)Nc1scnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C10H8N4O4S2/c15-5(3-6(16)17)13-9-7(12-4-20-9)8(18)14-10-11-1-2-19-10/h1-2,4H,3H2,(H,13,15)(H,16,17)(H,11,14,18)
PDB

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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.91E+3n/an/an/an/an/an/a



Graduate School of the Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)


Bioorg Med Chem Lett 15: 3732-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.055
BindingDB Entry DOI: 10.7270/Q2T1534B
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))
BDBM50169681
PNG
(CHEMBL178736 | N-[4-(Thiazol-2-ylcarbamoyl)-thiazo...)
Show SMILES OC(=O)CC(=O)Nc1scnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C10H8N4O4S2/c15-5(3-6(16)17)13-9-7(12-4-20-9)8(18)14-10-11-1-2-19-10/h1-2,4H,3H2,(H,13,15)(H,16,17)(H,11,14,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 88n/an/an/an/an/an/a



Graduate School of the Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)


Bioorg Med Chem Lett 15: 3732-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.055
BindingDB Entry DOI: 10.7270/Q2T1534B
More data for this
Ligand-Target Pair