BDBM50169684 5-(2-Chloro-4-fluoro-benzyl)-thiazole-4-carboxylic acid thiazol-2-ylamide::CHEMBL361978

SMILES: Fc1ccc(Cc2scnc2C(=O)Nc2nccs2)c(Cl)c1

InChI Key: InChIKey=GOJSWWPJAAVYDR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50169684 (5-(2-Chloro-4-fluoro-benzyl)-thiazole-4-carboxylic...) Show SMILES Fc1ccc(Cc2scnc2C(=O)Nc2nccs2)c(Cl)c1 Show InChI InChI=1S/C14H9ClFN3OS2/c15-10-6-9(16)2-1-8(10)5-11-12(18-7-22-11)13(20)19-14-17-3-4-21-14/h1-4,6-7H,5H2,(H,17,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Saccharomyces cerevisiae MetAP1 (330 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50169684 (5-(2-Chloro-4-fluoro-benzyl)-thiazole-4-carboxylic...) Show SMILES Fc1ccc(Cc2scnc2C(=O)Nc2nccs2)c(Cl)c1 Show InChI InChI=1S/C14H9ClFN3OS2/c15-10-6-9(16)2-1-8(10)5-11-12(18-7-22-11)13(20)19-14-17-3-4-21-14/h1-4,6-7H,5H2,(H,17,19,20)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of the Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory concentration required against Escherichia coli MetAP1 (150 nM)				Bioorg Med Chem Lett 15: 3732-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.055 BindingDB Entry DOI: 10.7270/Q2T1534B
					More data for this Ligand-Target Pair