BDBM50170406 5-(4-Chloro-phenyl)-5-oxo-pentanoic acid [4-(3-dimethylamino-pyrrolidin-1-yl)-phenyl]-amide::CHEMBL178882

SMILES: CN(C)C1CCN(C1)c1ccc(NC(=O)CCCC(=O)c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=IBWPEMBCMSWKSH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50170406 (5-(4-Chloro-phenyl)-5-oxo-pentanoic acid [4-(3-dim...) Show SMILES CN(C)C1CCN(C1)c1ccc(NC(=O)CCCC(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C23H28ClN3O2/c1-26(2)21-14-15-27(16-21)20-12-10-19(11-13-20)25-23(29)5-3-4-22(28)17-6-8-18(24)9-7-17/h6-13,21H,3-5,14-16H2,1-2H3,(H,25,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human MCH-R1 evaluated by its ability to displace radioligand [125I]-Tyr13]-MCH				Bioorg Med Chem Lett 15: 3701-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.130 BindingDB Entry DOI: 10.7270/Q29W0F16
					More data for this Ligand-Target Pair