BDBM50170695 (S)-1-{(S)-1-[3-(Pyrrolidine-1-carbonyl)-benzoyl]-pyrrolidine-2-carbonyl}-pyrrolidine-2-carbonitrile::CHEMBL191061

SMILES: O=C([C@@H]1CCCN1C(=O)c1cccc(c1)C(=O)N1CCCC1)N1CCC[C@H]1C#N

InChI Key: InChIKey=ZDXNXRUACQGMNP-OALUTQOASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Sus scrofa)	BDBM50170695 ((S)-1-{(S)-1-[3-(Pyrrolidine-1-carbonyl)-benzoyl]-...) Show SMILES O=C([C@@H]1CCCN1C(=O)c1cccc(c1)C(=O)N1CCCC1)N1CCC[C@H]1C#N Show InChI InChI=1S/C22H26N4O3/c23-15-18-8-4-12-25(18)22(29)19-9-5-13-26(19)21(28)17-7-3-6-16(14-17)20(27)24-10-1-2-11-24/h3,6-7,14,18-19H,1-2,4-5,8-13H2/t18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	7.0	n/a
University of Kuopio Curated by ChEMBL					Assay Description In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...				J Med Chem 48: 4772-82 (2005) Article DOI: 10.1021/jm0500020 BindingDB Entry DOI: 10.7270/Q22B8ZT2
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