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SMILES: CCOc1cc(Oc2cccnc2)cnc1Nc1cccc(C)n1

InChI Key: InChIKey=TVMWJBZCHSROEX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171065   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50171065
PNG
(CHEMBL366242 | [3-Ethoxy-5-(pyridin-3-yloxy)-pyrid...)
Show SMILES CCOc1cc(Oc2cccnc2)cnc1Nc1cccc(C)n1
Show InChI InChI=1S/C18H18N4O2/c1-3-23-16-10-15(24-14-7-5-9-19-11-14)12-20-18(16)22-17-8-4-6-13(2)21-17/h4-12H,3H2,1-2H3,(H,20,21,22)
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Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection

Bioorg Med Chem Lett 15: 4350-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.059
BindingDB Entry DOI: 10.7270/Q2QZ29H0
More data for this
Ligand-Target Pair