BDBM50171068 (3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-amine::CHEMBL196536

SMILES: COc1cccnc1Nc1cccc(C)n1

InChI Key: InChIKey=AXYSWEVLAQUWGT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amiloride-sensitive cation channel 3 (Homo sapiens (Human))	BDBM50171068 ((3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-a...) Show SMILES COc1cccnc1Nc1cccc(C)n1 Show InChI InChI=1S/C12H13N3O/c1-9-5-3-7-11(14-9)15-12-10(16-2)6-4-8-13-12/h3-8H,1-2H3,(H,13,14,15)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assay				Bioorg Med Chem Lett 21: 2646-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.115 BindingDB Entry DOI: 10.7270/Q2QV3MVJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171068 ((3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-a...) Show SMILES COc1cccnc1Nc1cccc(C)n1 Show InChI InChI=1S/C12H13N3O/c1-9-5-3-7-11(14-9)15-12-10(16-2)6-4-8-13-12/h3-8H,1-2H3,(H,13,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	458	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
					More data for this Ligand-Target Pair