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SMILES: Cc1cccc(Nc2ncccc2OCc2ccccc2)n1

InChI Key: InChIKey=OOQQSPQZOGECBR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50171072   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50171072
PNG
((3-Benzyloxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)...)
Show SMILES Cc1cccc(Nc2ncccc2OCc2ccccc2)n1
Show InChI InChI=1S/C18H17N3O/c1-14-7-5-11-17(20-14)21-18-16(10-6-12-19-18)22-13-15-8-3-2-4-9-15/h2-12H,13H2,1H3,(H,19,20,21)
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Article
PubMed
n/an/a 870n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection

Bioorg Med Chem Lett 15: 4350-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.059
BindingDB Entry DOI: 10.7270/Q2QZ29H0
More data for this
Ligand-Target Pair