null

SMILES: COc1ccc(NCc2cnc[nH]2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key: InChIKey=ACSHHJKLILVPFO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171573 (CHEMBL363169 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1ccc(NCc2cnc[nH]2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C25H29N5O4/c1-32-20-3-4-22(27-13-19-12-26-15-28-19)21(11-20)25(31)29-18-6-8-30(9-7-18)14-17-2-5-23-24(10-17)34-16-33-23/h2-5,10-12,15,18,27H,6-9,13-14,16H2,1H3,(H,26,28)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cells				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50171573 (CHEMBL363169 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES COc1ccc(NCc2cnc[nH]2)c(c1)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C25H29N5O4/c1-32-20-3-4-22(27-13-19-12-26-15-28-19)21(11-20)25(31)29-18-6-8-30(9-7-18)14-17-2-5-23-24(10-17)34-16-33-23/h2-5,10-12,15,18,27H,6-9,13-14,16H2,1H3,(H,26,28)(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against MCH1R IMR32 cells in FLIPR-based assay				Bioorg Med Chem Lett 15: 4174-9 (2005) Article DOI: 10.1016/j.bmcl.2005.06.089 BindingDB Entry DOI: 10.7270/Q2N29WGN
					More data for this Ligand-Target Pair