null

SMILES: COc1ccccc1N1CCN(CCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1

InChI Key: InChIKey=ZHQOLPARHMJYHA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50171893 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethoxy}...) Show SMILES COc1ccccc1N1CCN(CCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 |c:23| Show InChI InChI=1S/C22H27N3O4/c1-28-18-5-3-2-4-17(18)24-10-8-23(9-11-24)12-13-29-25-21(26)19-15-6-7-16(14-15)20(19)22(25)27/h2-7,15-16,19-20H,8-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Napoli "Federico II" Curated by ChEMBL					Assay Description Inhibition of [3H]-8-OH-DPAT binding to Serotonin 5-HT1A receptor from rat brain cortex				J Med Chem 48: 5495-503 (2005) Article DOI: 10.1021/jm050246k BindingDB Entry DOI: 10.7270/Q2TM79N5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50171893 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethoxy}...) Show SMILES COc1ccccc1N1CCN(CCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 |c:23| Show InChI InChI=1S/C22H27N3O4/c1-28-18-5-3-2-4-17(18)24-10-8-23(9-11-24)12-13-29-25-21(26)19-15-6-7-16(14-15)20(19)22(25)27/h2-7,15-16,19-20H,8-14H2,1H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Napoli "Federico II" Curated by ChEMBL					Assay Description Inhibition of 1 nM [3H]-mesulergine binding to Serotonin 5-HT2C receptor from rat brain cortex				J Med Chem 48: 5495-503 (2005) Article DOI: 10.1021/jm050246k BindingDB Entry DOI: 10.7270/Q2TM79N5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50171893 (4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethoxy}...) Show SMILES COc1ccccc1N1CCN(CCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 |c:23| Show InChI InChI=1S/C22H27N3O4/c1-28-18-5-3-2-4-17(18)24-10-8-23(9-11-24)12-13-29-25-21(26)19-15-6-7-16(14-15)20(19)22(25)27/h2-7,15-16,19-20H,8-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Napoli "Federico II" Curated by ChEMBL					Assay Description Inhibition of 0.4 nM [3H]-ketanserin binding to Serotonin 5-HT2A receptor from rat brain cortex				J Med Chem 48: 5495-503 (2005) Article DOI: 10.1021/jm050246k BindingDB Entry DOI: 10.7270/Q2TM79N5
					More data for this Ligand-Target Pair