BDBM50172088 (2R,4S)-2,4-dibenzyl-8-methyl-8-azabicyclo[3.2.1]octane::CHEMBL371493

SMILES: CN1C2CCC1[C@H](Cc1ccccc1)C[C@@H]2Cc1ccccc1

InChI Key: InChIKey=IVOKVSCIEVHNAL-FDRBHKFBSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50172088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vesicular monoamine transporter 2 (VMAT2) (Rattus norvegicus (Rat))	BDBM50172088 ((2R,4S)-2,4-dibenzyl-8-methyl-8-azabicyclo[3.2.1]o...) Show SMILES CN1C2CCC1[C@H](Cc1ccccc1)C[C@@H]2Cc1ccccc1 |TLB:7:6:1:4.3,THB:16:15:1:4.3| Show InChI InChI=1S/C22H27N/c1-23-21-12-13-22(23)20(15-18-10-6-3-7-11-18)16-19(21)14-17-8-4-2-5-9-17/h2-11,19-22H,12-16H2,1H3/t19-,20+,21?,22?	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-dihydrotetrabenazine binding to vesicular monoamine transporter-2 of rat synaptic vesicle membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair
Vesicular monoamine transporter 2 (VMAT2) (Rattus norvegicus (Rat))	BDBM50172088 ((2R,4S)-2,4-dibenzyl-8-methyl-8-azabicyclo[3.2.1]o...) Show SMILES CN1C2CCC1[C@H](Cc1ccccc1)C[C@@H]2Cc1ccccc1 |TLB:7:6:1:4.3,THB:16:15:1:4.3| Show InChI InChI=1S/C22H27N/c1-23-21-12-13-22(23)20(15-18-10-6-3-7-11-18)16-19(21)14-17-8-4-2-5-9-17/h2-11,19-22H,12-16H2,1H3/t19-,20+,21?,22?	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-nicotine binding to vesicular monoamine transporter-2 of rat brain membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair
Vesicular monoamine transporter 2 (VMAT2) (Rattus norvegicus (Rat))	BDBM50172088 ((2R,4S)-2,4-dibenzyl-8-methyl-8-azabicyclo[3.2.1]o...) Show SMILES CN1C2CCC1[C@H](Cc1ccccc1)C[C@@H]2Cc1ccccc1 |TLB:7:6:1:4.3,THB:16:15:1:4.3| Show InChI InChI=1S/C22H27N/c1-23-21-12-13-22(23)20(15-18-10-6-3-7-11-18)16-19(21)14-17-8-4-2-5-9-17/h2-11,19-22H,12-16H2,1H3/t19-,20+,21?,22?	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-methyllycaconitine binding to vesicular monoamine transporter-2 of rat brain membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair