null

SMILES: COc1ccc(C[C@H]2C=C(Cc3ccc(OC)cc3)C3CCC2N3C)cc1

InChI Key: InChIKey=IIUCDLSWGJQFQI-HLJPNSHOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50172092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50172092 ((S)-2,4-Bis-(4-methoxy-benzyl)-8-methyl-8-aza-bicy...) Show SMILES COc1ccc(C[C@H]2C=C(Cc3ccc(OC)cc3)C3CCC2N3C)cc1 |t:8,TLB:10:9:23:20.21,6:7:23:20.21| Show InChI InChI=1S/C24H29NO2/c1-25-23-12-13-24(25)20(15-18-6-10-22(27-3)11-7-18)16-19(23)14-17-4-8-21(26-2)9-5-17/h4-11,16,19,23-24H,12-15H2,1-3H3/t19-,23?,24?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-dihydrotetrabenazine binding to vesicular monoamine transporter-2 of rat synaptic vesicle membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50172092 ((S)-2,4-Bis-(4-methoxy-benzyl)-8-methyl-8-aza-bicy...) Show SMILES COc1ccc(C[C@H]2C=C(Cc3ccc(OC)cc3)C3CCC2N3C)cc1 |t:8,TLB:10:9:23:20.21,6:7:23:20.21| Show InChI InChI=1S/C24H29NO2/c1-25-23-12-13-24(25)20(15-18-6-10-22(27-3)11-7-18)16-19(23)14-17-4-8-21(26-2)9-5-17/h4-11,16,19,23-24H,12-15H2,1-3H3/t19-,23?,24?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-methyllycaconitine binding to vesicular monoamine transporter-2 of rat brain membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50172092 ((S)-2,4-Bis-(4-methoxy-benzyl)-8-methyl-8-aza-bicy...) Show SMILES COc1ccc(C[C@H]2C=C(Cc3ccc(OC)cc3)C3CCC2N3C)cc1 |t:8,TLB:10:9:23:20.21,6:7:23:20.21| Show InChI InChI=1S/C24H29NO2/c1-25-23-12-13-24(25)20(15-18-6-10-22(27-3)11-7-18)16-19(23)14-17-4-8-21(26-2)9-5-17/h4-11,16,19,23-24H,12-15H2,1-3H3/t19-,23?,24?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition constant against [3H]-nicotine binding to vesicular monoamine transporter-2 of rat brain membranes				Bioorg Med Chem Lett 15: 4463-6 (2005) Article DOI: 10.1016/j.bmcl.2005.07.032 BindingDB Entry DOI: 10.7270/Q2J38S3H
					More data for this Ligand-Target Pair