BindingDB PrimarySearch

null

SMILES: CCCN(CCC)[C@@H]1CCn2nccc2C1

InChI Key: InChIKey=LVAZPFMWSRDRRK-GFCCVEGCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50172509
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 mins				J Med Chem 54: 2477-91 (2011) Article DOI: 10.1021/jm101639t BindingDB Entry DOI: 10.7270/Q2V1253W
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor 3 expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligand				J Med Chem 48: 5771-9 (2005) Article DOI: 10.1021/jm0503805 BindingDB Entry DOI: 10.7270/Q2KW5GT9
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D3 receptor expressed in CHO cells after 60 mins				J Med Chem 54: 2477-91 (2011) Article DOI: 10.1021/jm101639t BindingDB Entry DOI: 10.7270/Q2V1253W
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor 4.4 expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligand				J Med Chem 48: 5771-9 (2005) Article DOI: 10.1021/jm0503805 BindingDB Entry DOI: 10.7270/Q2KW5GT9
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Sus scrofa)	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Binding affinity towards porcine dopamine receptor 1 against radioligand [3H]-SCH- 23390				J Med Chem 48: 5771-9 (2005) Article DOI: 10.1021/jm0503805 BindingDB Entry DOI: 10.7270/Q2KW5GT9
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor 2 (short) expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligand				J Med Chem 48: 5771-9 (2005) Article DOI: 10.1021/jm0503805 BindingDB Entry DOI: 10.7270/Q2KW5GT9
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor 2 (long) expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligand				J Med Chem 48: 5771-9 (2005) Article DOI: 10.1021/jm0503805 BindingDB Entry DOI: 10.7270/Q2KW5GT9
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cells after 60 mins				J Med Chem 54: 2477-91 (2011) Article DOI: 10.1021/jm101639t BindingDB Entry DOI: 10.7270/Q2V1253W
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells after 60 mins				J Med Chem 54: 2477-91 (2011) Article DOI: 10.1021/jm101639t BindingDB Entry DOI: 10.7270/Q2V1253W
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2long receptor expressed in CHO cells after 60 mins				J Med Chem 54: 2477-91 (2011) Article DOI: 10.1021/jm101639t BindingDB Entry DOI: 10.7270/Q2V1253W
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Sus scrofa)	BDBM50172509 (CHEMBL197159 \| Dipropyl-(R)-4,5,6,7-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@@H]1CCn2nccc2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine cerebral cortex after 60 mins				J Med Chem 54: 2477-91 (2011) Article DOI: 10.1021/jm101639t BindingDB Entry DOI: 10.7270/Q2V1253W
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair