BDBM50172766 3-(3-Methylamino-propyl)-1-phenyl-3-propyl-3,4-dihydro-1H-quinolin-2-one::CHEMBL198960

SMILES: CCCC1(CCCNC)Cc2ccccc2N(C1=O)c1ccccc1

InChI Key: InChIKey=LQONCZWYZLNINV-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50172766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50172766 (3-(3-Methylamino-propyl)-1-phenyl-3-propyl-3,4-dih...) Show SMILES CCCC1(CCCNC)Cc2ccccc2N(C1=O)c1ccccc1 Show InChI InChI=1S/C22H28N2O/c1-3-14-22(15-9-16-23-2)17-18-10-7-8-13-20(18)24(21(22)25)19-11-5-4-6-12-19/h4-8,10-13,23H,3,9,14-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Ltd Curated by ChEMBL					Assay Description Inhibition of monoamine reuptake at norepinephrine transporter				Bioorg Med Chem Lett 15: 4432-7 (2005) Article DOI: 10.1016/j.bmcl.2005.07.038 BindingDB Entry DOI: 10.7270/Q2G44PTW
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50172766 (3-(3-Methylamino-propyl)-1-phenyl-3-propyl-3,4-dih...) Show SMILES CCCC1(CCCNC)Cc2ccccc2N(C1=O)c1ccccc1 Show InChI InChI=1S/C22H28N2O/c1-3-14-22(15-9-16-23-2)17-18-10-7-8-13-20(18)24(21(22)25)19-11-5-4-6-12-19/h4-8,10-13,23H,3,9,14-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Ltd Curated by ChEMBL					Assay Description Inhibitio of monoamine reuptake at serotonin transporter				Bioorg Med Chem Lett 15: 4432-7 (2005) Article DOI: 10.1016/j.bmcl.2005.07.038 BindingDB Entry DOI: 10.7270/Q2G44PTW
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50172766 (3-(3-Methylamino-propyl)-1-phenyl-3-propyl-3,4-dih...) Show SMILES CCCC1(CCCNC)Cc2ccccc2N(C1=O)c1ccccc1 Show InChI InChI=1S/C22H28N2O/c1-3-14-22(15-9-16-23-2)17-18-10-7-8-13-20(18)24(21(22)25)19-11-5-4-6-12-19/h4-8,10-13,23H,3,9,14-17H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Ltd Curated by ChEMBL					Assay Description Inhibition of monoamine reuptake at dopamine transporter				Bioorg Med Chem Lett 15: 4432-7 (2005) Article DOI: 10.1016/j.bmcl.2005.07.038 BindingDB Entry DOI: 10.7270/Q2G44PTW
					More data for this Ligand-Target Pair