BDBM50173018 CHEMBL195829::N-(4-(chlorodifluoromethoxy)phenyl)-4-(4-methoxyphenyl)phthalazin-1-amine::[4-(Chloro-difluoro-methoxy)-phenyl]-[4-(4-methoxy-phenyl)-phthalazin-1-yl]-amine

SMILES: COc1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12

InChI Key: InChIKey=KFJAJDCTCQRIBZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173018 (CHEMBL195829 | N-(4-(chlorodifluoromethoxy)phenyl)...) Show SMILES COc1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H16ClF2N3O2/c1-29-16-10-6-14(7-11-16)20-18-4-2-3-5-19(18)21(28-27-20)26-15-8-12-17(13-9-15)30-22(23,24)25/h2-13H,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF method				Bioorg Med Chem 17: 731-40 (2009) Article DOI: 10.1016/j.bmc.2008.11.049 BindingDB Entry DOI: 10.7270/Q2W95929
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173018 (CHEMBL195829 | N-(4-(chlorodifluoromethoxy)phenyl)...) Show SMILES COc1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H16ClF2N3O2/c1-29-16-10-6-14(7-11-16)20-18-4-2-3-5-19(18)21(28-27-20)26-15-8-12-17(13-9-15)30-22(23,24)25/h2-13H,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide				Bioorg Med Chem Lett 15: 4696-8 (2005) Article DOI: 10.1016/j.bmcl.2005.07.064 BindingDB Entry DOI: 10.7270/Q25Q4VNS
					More data for this Ligand-Target Pair