BDBM50173027 CHEMBL196940::N,N-Dimethyl-4-(4-p-tolylamino-phthalazin-1-yl)-benzamide

SMILES: CN(C)C(=O)c1ccc(cc1)-c1nnc(Nc2ccc(C)cc2)c2ccccc12

InChI Key: InChIKey=BAQDBPNONPOWJQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173027 (CHEMBL196940 | N,N-Dimethyl-4-(4-p-tolylamino-phth...) Show SMILES CN(C)C(=O)c1ccc(cc1)-c1nnc(Nc2ccc(C)cc2)c2ccccc12 Show InChI InChI=1S/C24H22N4O/c1-16-8-14-19(15-9-16)25-23-21-7-5-4-6-20(21)22(26-27-23)17-10-12-18(13-11-17)24(29)28(2)3/h4-15H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide				Bioorg Med Chem Lett 15: 4696-8 (2005) Article DOI: 10.1016/j.bmcl.2005.07.064 BindingDB Entry DOI: 10.7270/Q25Q4VNS
					More data for this Ligand-Target Pair