BDBM50173038 (3,4-Dichloro-phenyl)-(4-p-tolyl-phthalazin-1-yl)-amine::CHEMBL193705

SMILES: Cc1ccc(cc1)-c1nnc(Nc2ccc(Cl)c(Cl)c2)c2ccccc12

InChI Key: InChIKey=LSCYFDLABPHDDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50173038 ((3,4-Dichloro-phenyl)-(4-p-tolyl-phthalazin-1-yl)-...) Show SMILES Cc1ccc(cc1)-c1nnc(Nc2ccc(Cl)c(Cl)c2)c2ccccc12 Show InChI InChI=1S/C21H15Cl2N3/c1-13-6-8-14(9-7-13)20-16-4-2-3-5-17(16)21(26-25-20)24-15-10-11-18(22)19(23)12-15/h2-12H,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide				Bioorg Med Chem Lett 15: 4696-8 (2005) Article DOI: 10.1016/j.bmcl.2005.07.064 BindingDB Entry DOI: 10.7270/Q25Q4VNS
					More data for this Ligand-Target Pair