BDBM50173146 4-(4-Benzyloxy-3,5-dibromo-phenylcarbamoyl)-2,5-dihydro-thiophene-3-carboxylic acid::CHEMBL195246

SMILES: OC(=O)C1=C(CSC1)C(=O)Nc1cc(Br)c(OCc2ccccc2)c(Br)c1

InChI Key: InChIKey=KIZKQKCZXNHFRK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50173146 (4-(4-Benzyloxy-3,5-dibromo-phenylcarbamoyl)-2,5-di...) Show SMILES OC(=O)C1=C(CSC1)C(=O)Nc1cc(Br)c(OCc2ccccc2)c(Br)c1 |t:3| Show InChI InChI=1S/C19H15Br2NO4S/c20-15-6-12(22-18(23)13-9-27-10-14(13)19(24)25)7-16(21)17(15)26-8-11-4-2-1-3-5-11/h1-7H,8-10H2,(H,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
4SC AG Curated by ChEMBL					Assay Description Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assay				Bioorg Med Chem Lett 15: 4854-7 (2005) Article DOI: 10.1016/j.bmcl.2005.07.053 BindingDB Entry DOI: 10.7270/Q2HX1C7N
					More data for this Ligand-Target Pair