BindingDB logo
myBDB logout

null

SMILES: OC(=O)C1=C(COC1)C(=O)Nc1c(F)cc(cc1F)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=MSTKYRFDVPTMGG-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50173160   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50173160
PNG
(4-(3,5-Difluoro-3'-trifluoromethoxy-biphenyl-4-ylc...)
Show SMILES OC(=O)C1=C(COC1)C(=O)Nc1c(F)cc(cc1F)-c1cccc(OC(F)(F)F)c1 |t:3|
Show InChI InChI=1S/C19H12F5NO5/c20-14-5-10(9-2-1-3-11(4-9)30-19(22,23)24)6-15(21)16(14)25-17(26)12-7-29-8-13(12)18(27)28/h1-6H,7-8H2,(H,25,26)(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 205n/an/an/an/an/an/a



4SC AG

Curated by ChEMBL


Assay Description
Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assay

Bioorg Med Chem Lett 15: 4854-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.053
BindingDB Entry DOI: 10.7270/Q2HX1C7N
More data for this
Ligand-Target Pair