BDBM50173267 1'-cyclooctylmethyl-1-(2-hydroxyethyl)spiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-2-one::CHEMBL380603

SMILES: OCCN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccccc12

InChI Key: InChIKey=IXGOFFNUXCZZJI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50173267 (1'-cyclooctylmethyl-1-(2-hydroxyethyl)spiro[2,3-di...) Show SMILES OCCN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccccc12 Show InChI InChI=1S/C23H34N2O2/c26-17-16-25-21-11-7-6-10-20(21)23(22(25)27)12-14-24(15-13-23)18-19-8-4-2-1-3-5-9-19/h6-7,10-11,19,26H,1-5,8-9,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...				Bioorg Med Chem Lett 15: 5022-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.009 BindingDB Entry DOI: 10.7270/Q2RF5TKC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50173267 (1'-cyclooctylmethyl-1-(2-hydroxyethyl)spiro[2,3-di...) Show SMILES OCCN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccccc12 Show InChI InChI=1S/C23H34N2O2/c26-17-16-25-21-11-7-6-10-20(21)23(22(25)27)12-14-24(15-13-23)18-19-8-4-2-1-3-5-9-19/h6-7,10-11,19,26H,1-5,8-9,12-18H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligand				Bioorg Med Chem Lett 15: 5022-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.009 BindingDB Entry DOI: 10.7270/Q2RF5TKC
					More data for this Ligand-Target Pair