BDBM50173537 CHEMBL197746::Sulfamic acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester

SMILES: NS(=O)(=O)OCC1OC(C=C1)n1ccc(=O)[nH]c1=O

InChI Key: InChIKey=JNTYPENMQJEONP-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
dUTP pyrophosphatase (Plasmodium falciparum)	BDBM50173537 (CHEMBL197746 | Sulfamic acid 5-(2,4-dioxo-3,4-dihy...) Show SMILES NS(=O)(=O)OCC1OC(C=C1)n1ccc(=O)[nH]c1=O |c:9| Show InChI InChI=1S/C9H11N3O6S/c10-19(15,16)17-5-6-1-2-8(18-6)12-4-3-7(13)11-9(12)14/h1-4,6,8H,5H2,(H2,10,15,16)(H,11,13,14)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.54E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cells				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (Homo sapiens (Human))	BDBM50173537 (CHEMBL197746 | Sulfamic acid 5-(2,4-dioxo-3,4-dihy...) Show SMILES NS(=O)(=O)OCC1OC(C=C1)n1ccc(=O)[nH]c1=O |c:9| Show InChI InChI=1S/C9H11N3O6S/c10-19(15,16)17-5-6-1-2-8(18-6)12-4-3-7(13)11-9(12)14/h1-4,6,8H,5H2,(H2,10,15,16)(H,11,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cells				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair
dUTP pyrophosphatase (Leishmania major)	BDBM50173537 (CHEMBL197746 | Sulfamic acid 5-(2,4-dioxo-3,4-dihy...) Show SMILES NS(=O)(=O)OCC1OC(C=C1)n1ccc(=O)[nH]c1=O |c:9| Show InChI InChI=1S/C9H11N3O6S/c10-19(15,16)17-5-6-1-2-8(18-6)12-4-3-7(13)11-9(12)14/h1-4,6,8H,5H2,(H2,10,15,16)(H,11,13,14)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolase				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair