BDBM50173541 Acetic acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester::CHEMBL3143778

SMILES: CC(=O)OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O

InChI Key: InChIKey=WSBRDNULWYNRFT-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
dUTP pyrophosphatase (Plasmodium falciparum)	BDBM50173541 (Acetic acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-...) Show SMILES CC(=O)OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C11H14N2O6/c1-6(14)18-5-8-7(15)4-10(19-8)13-3-2-9(16)12-11(13)17/h2-3,7-8,10,15H,4-5H2,1H3,(H,12,16,17)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.94E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cells				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (Homo sapiens (Human))	BDBM50173541 (Acetic acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-...) Show SMILES CC(=O)OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C11H14N2O6/c1-6(14)18-5-8-7(15)4-10(19-8)13-3-2-9(16)12-11(13)17/h2-3,7-8,10,15H,4-5H2,1H3,(H,12,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cells				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair
dUTP pyrophosphatase (Leishmania major)	BDBM50173541 (Acetic acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-...) Show SMILES CC(=O)OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C11H14N2O6/c1-6(14)18-5-8-7(15)4-10(19-8)13-3-2-9(16)12-11(13)17/h2-3,7-8,10,15H,4-5H2,1H3,(H,12,16,17)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolase				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair