BDBM50173549 CHEMBL3143776::Phosphoric acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester diethyl ester

SMILES: CCOP(=O)(OCC)OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O

InChI Key: InChIKey=IHNMQYODZISEAH-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
dUTP pyrophosphatase (Plasmodium falciparum)	BDBM50173549 (CHEMBL3143776 | Phosphoric acid 5-(2,4-dioxo-3,4-d...) Show SMILES CCOP(=O)(OCC)OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C13H21N2O8P/c1-3-20-24(19,21-4-2)22-8-10-9(16)7-12(23-10)15-6-5-11(17)14-13(15)18/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3,(H,14,17,18)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cells				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair
dUTP pyrophosphatase (Leishmania major)	BDBM50173549 (CHEMBL3143776 | Phosphoric acid 5-(2,4-dioxo-3,4-d...) Show SMILES CCOP(=O)(OCC)OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C13H21N2O8P/c1-3-20-24(19,21-4-2)22-8-10-9(16)7-12(23-10)15-6-5-11(17)14-13(15)18/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3,(H,14,17,18)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolase				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (Homo sapiens (Human))	BDBM50173549 (CHEMBL3143776 | Phosphoric acid 5-(2,4-dioxo-3,4-d...) Show SMILES CCOP(=O)(OCC)OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C13H21N2O8P/c1-3-20-24(19,21-4-2)22-8-10-9(16)7-12(23-10)15-6-5-11(17)14-13(15)18/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3,(H,14,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cells				J Med Chem 48: 5942-54 (2005) Article DOI: 10.1021/jm050111e BindingDB Entry DOI: 10.7270/Q2Z320DG
					More data for this Ligand-Target Pair