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SMILES: Oc1ccccc1CNC1CCN(CC1)S(=O)(=O)Nc1cccc(Oc2ccccc2)c1

InChI Key: InChIKey=GXJYTKZEZLRQTD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174089   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50174089
PNG
(4-(2-hydroxybenzylamino)-N-(3-phenoxyphenyl)piperi...)
Show SMILES Oc1ccccc1CNC1CCN(CC1)S(=O)(=O)Nc1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C24H27N3O4S/c28-24-12-5-4-7-19(24)18-25-20-13-15-27(16-14-20)32(29,30)26-21-8-6-11-23(17-21)31-22-9-2-1-3-10-22/h1-12,17,20,25-26,28H,13-16,18H2
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Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Locus Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against p38alpha MAPK

Bioorg Med Chem Lett 15: 5274-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.038
BindingDB Entry DOI: 10.7270/Q24J0DP9
More data for this
Ligand-Target Pair