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SMILES: CC(C)(CO)c1ccc(CNC(=O)c2ccc(Oc3ccccc3)cc2)cc1O

InChI Key: InChIKey=HOUXGOLWMLYROP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174092   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50174092
PNG
(CHEMBL199229 | N-(3-hydroxy-4-(1-hydroxy-2-methylp...)
Show SMILES CC(C)(CO)c1ccc(CNC(=O)c2ccc(Oc3ccccc3)cc2)cc1O
Show InChI InChI=1S/C24H25NO4/c1-24(2,16-26)21-13-8-17(14-22(21)27)15-25-23(28)18-9-11-20(12-10-18)29-19-6-4-3-5-7-19/h3-14,26-27H,15-16H2,1-2H3,(H,25,28)
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Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Locus Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against p38alpha MAPK

Bioorg Med Chem Lett 15: 5274-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.038
BindingDB Entry DOI: 10.7270/Q24J0DP9
More data for this
Ligand-Target Pair