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SMILES: Oc1ccccc1CNC1CCN(CC1)S(=O)(=O)Nc1cccc(Oc2cccc(c2)C(F)(F)F)c1

InChI Key: InChIKey=DUHDSKMCOPWGII-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174093   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50174093
PNG
(4-(2-hydroxybenzylamino)-N-(3-(3-(trifluoromethyl)...)
Show SMILES Oc1ccccc1CNC1CCN(CC1)S(=O)(=O)Nc1cccc(Oc2cccc(c2)C(F)(F)F)c1
Show InChI InChI=1S/C25H26F3N3O4S/c26-25(27,28)19-6-3-8-22(15-19)35-23-9-4-7-21(16-23)30-36(33,34)31-13-11-20(12-14-31)29-17-18-5-1-2-10-24(18)32/h1-10,15-16,20,29-30,32H,11-14,17H2
PDB
MMDB

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Similars
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Locus Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against p38alpha MAPK

Bioorg Med Chem Lett 15: 5274-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.038
BindingDB Entry DOI: 10.7270/Q24J0DP9
More data for this
Ligand-Target Pair