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SMILES: Oc1ccccc1CNC1CCN(CC1)S(=O)(=O)Nc1cccc(Oc2ccccc2Cl)c1

InChI Key: InChIKey=BROPCELRIQFXIM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174094   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50174094
PNG
(4-(2-hydroxybenzylamino)-N-(3-(2-chlorophenoxy)phe...)
Show SMILES Oc1ccccc1CNC1CCN(CC1)S(=O)(=O)Nc1cccc(Oc2ccccc2Cl)c1
Show InChI InChI=1S/C24H26ClN3O4S/c25-22-9-2-4-11-24(22)32-21-8-5-7-20(16-21)27-33(30,31)28-14-12-19(13-15-28)26-17-18-6-1-3-10-23(18)29/h1-11,16,19,26-27,29H,12-15,17H2
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Similars
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Locus Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against p38alpha MAPK

Bioorg Med Chem Lett 15: 5274-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.038
BindingDB Entry DOI: 10.7270/Q24J0DP9
More data for this
Ligand-Target Pair