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SMILES: COc1cc2NC3(Cc4ccsc4C3)N(C)C(=O)c2cc1-c1cnco1

InChI Key: InChIKey=JGCILFCSMGUNBX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174781   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50174781
PNG
(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-3',4',1,...)
Show SMILES COc1cc2NC3(Cc4ccsc4C3)N(C)C(=O)c2cc1-c1cnco1
Show InChI InChI=1S/C19H17N3O3S/c1-22-18(23)12-5-13(16-9-20-10-25-16)15(24-2)6-14(12)21-19(22)7-11-3-4-26-17(11)8-19/h3-6,9-10,21H,7-8H2,1-2H3
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MMDB

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n/an/a 96n/an/an/an/an/an/a



UCB Celltech

Curated by ChEMBL


Assay Description
Inhibitory activity against IMPDH II

Bioorg Med Chem Lett 15: 5335-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.108
BindingDB Entry DOI: 10.7270/Q2CZ36P8
More data for this
Ligand-Target Pair