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SMILES: COc1cc2NC(C)(C)N(C)C(=O)c2cc1-c1cnco1

InChI Key: InChIKey=ILQYAJBFYVTASH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174786   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50174786
PNG
(7-methoxy-2,2,3-trimethyl-6-(oxazol-5-yl)-2,3-dihy...)
Show SMILES COc1cc2NC(C)(C)N(C)C(=O)c2cc1-c1cnco1
Show InChI InChI=1S/C15H17N3O3/c1-15(2)17-11-6-12(20-4)10(13-7-16-8-21-13)5-9(11)14(19)18(15)3/h5-8,17H,1-4H3
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MMDB

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n/an/a 192n/an/an/an/an/an/a



UCB Celltech

Curated by ChEMBL


Assay Description
Inhibitory activity against IMPDH II

Bioorg Med Chem Lett 15: 5335-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.108
BindingDB Entry DOI: 10.7270/Q2CZ36P8
More data for this
Ligand-Target Pair