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SMILES: COc1cc2NC3(CCN(C3)C(=O)N3CCCCC3)N(C)C(=O)c2cc1-c1cnco1

InChI Key: InChIKey=RNJIYWDDFNGEMY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174795   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50174795
PNG
(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-1-[(pipe...)
Show SMILES COc1cc2NC3(CCN(C3)C(=O)N3CCCCC3)N(C)C(=O)c2cc1-c1cnco1
Show InChI InChI=1S/C22H27N5O4/c1-25-20(28)15-10-16(19-12-23-14-31-19)18(30-2)11-17(15)24-22(25)6-9-27(13-22)21(29)26-7-4-3-5-8-26/h10-12,14,24H,3-9,13H2,1-2H3
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UCB Celltech

Curated by ChEMBL


Assay Description
Inhibitory activity against IMPDH II

Bioorg Med Chem Lett 15: 5335-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.108
BindingDB Entry DOI: 10.7270/Q2CZ36P8
More data for this
Ligand-Target Pair