BDBM50174885 Bu-5BrAtc-DPhe-Arg-2-Nal-Z9-NH2::CHEMBL200449

SMILES: [#6]-[#6]-[#6]-[#6](=O)-[#7]C1([#6]-[#6]-c2c(Br)cccc2-[#6]1)[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6](-[#6]-c1ccc2ccccc2c1)-[#6](=O)-[#7]-c1ccccc1-[#6](-[#7])=O

InChI Key: InChIKey=FATOKLBGGVMETM-RVUGNGSVSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50174885 (Bu-5BrAtc-DPhe-Arg-2-Nal-Z9-NH2 | CHEMBL200449) Show SMILES [#6]-[#6]-[#6]-[#6](=O)-[#7]C1([#6]-[#6]-c2c(Br)cccc2-[#6]1)[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6](-[#6]-c1ccc2ccccc2c1)-[#6](=O)-[#7]-c1ccccc1-[#6](-[#7])=O Show InChI InChI=1S/C50H56BrN9O6/c1-2-12-43(61)60-50(25-24-36-35(30-50)17-10-19-38(36)51)48(66)59-42(28-31-13-4-3-5-14-31)47(65)57-40(21-11-26-55-49(53)54)45(63)58-41(29-32-22-23-33-15-6-7-16-34(33)27-32)46(64)56-39-20-9-8-18-37(39)44(52)62/h3-10,13-20,22-23,27,40-42H,2,11-12,21,24-26,28-30H2,1H3,(H2,52,62)(H,56,64)(H,57,65)(H,58,63)(H,59,66)(H,60,61)(H4,53,54,55)/t40-,41?,42+,50?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Agonist activity in HEK293 cells transfected with human MC4R by cAMP accumulation				Bioorg Med Chem Lett 15: 5504-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.083 BindingDB Entry DOI: 10.7270/Q2MC8ZK7
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