BDBM50174994 CHEMBL3809332

SMILES: Clc1ccc(Oc2cccc(CC3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1

InChI Key: InChIKey=UQQRKBSIKSUFPE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50174994 (CHEMBL3809332) Show SMILES Clc1ccc(Oc2cccc(CC3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-6-8-22(9-7-20)30-23-5-1-3-19(16-23)15-18-10-13-28(14-11-18)24(29)27-21-4-2-12-26-17-21/h1-9,12,16-18H,10-11,13-15H2,(H,27,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	215	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL					Assay Description Apparent inhibition of recombinant rat FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation anal...				Bioorg Med Chem Lett 26: 3109-14 (2016) BindingDB Entry DOI: 10.7270/Q25B04F3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50174994 (CHEMBL3809332) Show SMILES Clc1ccc(Oc2cccc(CC3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-6-8-22(9-7-20)30-23-5-1-3-19(16-23)15-18-10-13-28(14-11-18)24(29)27-21-4-2-12-26-17-21/h1-9,12,16-18H,10-11,13-15H2,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL					Assay Description Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an...				Bioorg Med Chem Lett 26: 3109-14 (2016) BindingDB Entry DOI: 10.7270/Q25B04F3
					More data for this Ligand-Target Pair