BDBM50175072 (S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acetic acid::CHEMBL197976

SMILES: N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O

InChI Key: InChIKey=KZOMBNQLBSHMFV-HZLVTQRSSA-N

Data: 2 KI  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50175072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM50175072 ((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...) Show SMILES N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-4(5(7)8)2-1-3(2)12(9,10)11/h2-4H,1,6H2,(H,7,8)(H2,9,10,11)/t2-,3-,4-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Displacement of [3H]L-AP4 from rat mGluR4 expressed in BHK cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (mGlu8) (Rattus norvegicus (Rat))	BDBM50175072 ((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...) Show SMILES N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-4(5(7)8)2-1-3(2)12(9,10)11/h2-4H,1,6H2,(H,7,8)(H2,9,10,11)/t2-,3-,4-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Displacement of [3H]LY341495 from rat mGluR8 expressed in BHK cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (RAT)	BDBM50175072 ((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...) Show SMILES N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-4(5(7)8)2-1-3(2)12(9,10)11/h2-4H,1,6H2,(H,7,8)(H2,9,10,11)/t2-,3-,4-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat mGluR1 by measuring intracellular calcium concentration in CHO cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
					More data for this Ligand-Target Pair
GRM7 (Homo sapiens (Human))	BDBM50175072 ((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...) Show SMILES N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-4(5(7)8)2-1-3(2)12(9,10)11/h2-4H,1,6H2,(H,7,8)(H2,9,10,11)/t2-,3-,4-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.00E+5	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at human mGluR7 by measuring cAMP formation in BHK cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM50175072 ((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...) Show SMILES N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-4(5(7)8)2-1-3(2)12(9,10)11/h2-4H,1,6H2,(H,7,8)(H2,9,10,11)/t2-,3-,4-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Functional activity at rat mGluR4				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50175072 ((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...) Show SMILES N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-4(5(7)8)2-1-3(2)12(9,10)11/h2-4H,1,6H2,(H,7,8)(H2,9,10,11)/t2-,3-,4-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat mGluR5 by measuring intracellular calcium concentration in CHO cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (mGlu6) (Rattus norvegicus (Rat))	BDBM50175072 ((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...) Show SMILES N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-4(5(7)8)2-1-3(2)12(9,10)11/h2-4H,1,6H2,(H,7,8)(H2,9,10,11)/t2-,3-,4-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat mGluR6 by measuring cAMP formation in CHO cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50175072 ((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...) Show SMILES N[C@@H]([C@H]1C[C@@H]1P(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H10NO5P/c6-4(5(7)8)2-1-3(2)12(9,10)11/h2-4H,1,6H2,(H,7,8)(H2,9,10,11)/t2-,3-,4-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at human mGluR2 from BHK cells in [35S]GTP-gamma-S stimulation assay				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
					More data for this Ligand-Target Pair