BDBM50175375 (S)-2-(3-(1-(benzo[b]thiophen-2-yl)-2-methylpropan-2-ylamino)-2-hydroxypropoxy)benzonitrile::CHEMBL199894

SMILES: CC(C)(Cc1cc2ccccc2s1)NC[C@H](O)COc1ccccc1C#N

InChI Key: InChIKey=QDANYWJDGOEFMO-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50175375 ((S)-2-(3-(1-(benzo[b]thiophen-2-yl)-2-methylpropan...) Show SMILES CC(C)(Cc1cc2ccccc2s1)NC[C@H](O)COc1ccccc1C#N Show InChI InChI=1S/C22H24N2O2S/c1-22(2,12-19-11-16-7-4-6-10-21(16)27-19)24-14-18(25)15-26-20-9-5-3-8-17(20)13-23/h3-11,18,24-25H,12,14-15H2,1-2H3/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR				Bioorg Med Chem Lett 15: 5478-82 (2005) Article DOI: 10.1016/j.bmcl.2005.08.095 BindingDB Entry DOI: 10.7270/Q2WS8STX
					More data for this Ligand-Target Pair