BDBM50175425 5-(2-chlorophenyl)furan-2-carbohydrazide::CHEMBL200849

SMILES: NNC(=O)c1ccc(o1)-c1ccccc1Cl

InChI Key: InChIKey=XQMRHWSGTVEDFG-UHFFFAOYSA-N

Data: 9 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50175425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	6.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Mn(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	7.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Co(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	5.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Ni(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Fe(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	7.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 100 uM Cobalt				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 5 uM Manganese				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	5.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 10 uM Nickel				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	6.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 100 uM Manganese				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175425 (5-(2-chlorophenyl)furan-2-carbohydrazide | CHEMBL2...) Show SMILES NNC(=O)c1ccc(o1)-c1ccccc1Cl Show InChI InChI=1S/C11H9ClN2O2/c12-8-4-2-1-3-7(8)9-5-6-10(16-9)11(15)14-13/h1-6H,13H2,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Inhibition of Escherichia coli methionine aminopeptidase in presence of 6 uM Iron				J Med Chem 50: 5735-42 (2007) Article DOI: 10.1021/jm700930k BindingDB Entry DOI: 10.7270/Q2JQ10R2
					More data for this Ligand-Target Pair				3D Structure (crystal)