BDBM50175835 3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(3-chlorophenyl)-3-oxopropanamide::CHEMBL372772

SMILES: Clc1cccc(NC(=O)CC(=O)N2CCC(Cc3cnc[nH]3)CC2)c1

InChI Key: InChIKey=FEFALLOOHWPKHT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HRH3 (GUINEA PIG)	BDBM50175835 (3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(...) Show SMILES Clc1cccc(NC(=O)CC(=O)N2CCC(Cc3cnc[nH]3)CC2)c1 Show InChI InChI=1S/C18H21ClN4O2/c19-14-2-1-3-15(9-14)22-17(24)10-18(25)23-6-4-13(5-7-23)8-16-11-20-12-21-16/h1-3,9,11-13H,4-8,10H2,(H,20,21)(H,22,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 16: 395-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.076 BindingDB Entry DOI: 10.7270/Q29S1QK1
					More data for this Ligand-Target Pair