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SMILES: Clc1ccc(NS(=O)(=O)CCN2CCC(Cc3cnc[nH]3)CC2)cc1

InChI Key: InChIKey=OUGIVMKXKQCERN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175853   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(GUINEA PIG)		BDBM50175853
PNG
(2-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)-N-(...)
Show SMILES Clc1ccc(NS(=O)(=O)CCN2CCC(Cc3cnc[nH]3)CC2)cc1
Show InChI InChI=1S/C17H23ClN4O2S/c18-15-1-3-16(4-2-15)21-25(23,24)10-9-22-7-5-14(6-8-22)11-17-12-19-13-20-17/h1-4,12-14,21H,5-11H2,(H,19,20)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
 170n/an/an/an/an/an/an/an/a



The Schering Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 16: 395-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.076
BindingDB Entry DOI: 10.7270/Q29S1QK1
More data for this
Ligand-Target Pair