BDBM50175856 CHEMBL200519::N-(2-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)ethyl)-4-chlorobenzamide

SMILES: Clc1ccc(cc1)C(=O)NCCN1CCC(Cc2cnc[nH]2)CC1

InChI Key: InChIKey=YTGVZVLIORPGHV-UHFFFAOYSA-N

Data: 1 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (GUINEA PIG)	BDBM50175856 (CHEMBL200519 | N-(2-(4-((1H-imidazol-4-yl)methyl)p...) Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C18H23ClN4O/c19-16-3-1-15(2-4-16)18(24)21-7-10-23-8-5-14(6-9-23)11-17-12-20-13-22-17/h1-4,12-14H,5-11H2,(H,20,22)(H,21,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 16: 395-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.076 BindingDB Entry DOI: 10.7270/Q29S1QK1
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50175856 (CHEMBL200519 | N-(2-(4-((1H-imidazol-4-yl)methyl)p...) Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C18H23ClN4O/c19-16-3-1-15(2-4-16)18(24)21-7-10-23-8-5-14(6-9-23)11-17-12-20-13-22-17/h1-4,12-14H,5-11H2,(H,20,22)(H,21,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Antagonist potency against histamine H3 receptor in an electrically stimulated guinea pig ileum				Bioorg Med Chem Lett 16: 395-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.076 BindingDB Entry DOI: 10.7270/Q29S1QK1
					More data for this Ligand-Target Pair