BDBM50176084 6-(3-Ethyl-4-methyl-phenylamino)-3-(10-hydroxy-decyl)-1H-pyrimidine-2,4-dione::CHEMBL198437

SMILES: CCc1cc(Nc2cc(=O)n(CCCCCCCCCCO)c(=O)[nH]2)ccc1C

InChI Key: InChIKey=RRIGEJMJNAQMHD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase IIIC (Bacillus subtilis)	BDBM50176084 (6-(3-Ethyl-4-methyl-phenylamino)-3-(10-hydroxy-dec...) Show SMILES CCc1cc(Nc2cc(=O)n(CCCCCCCCCCO)c(=O)[nH]2)ccc1C Show InChI InChI=1S/C23H35N3O3/c1-3-19-16-20(13-12-18(19)2)24-21-17-22(28)26(23(29)25-21)14-10-8-6-4-5-7-9-11-15-27/h12-13,16-17,24,27H,3-11,14-15H2,1-2H3,(H,25,29)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against Bacillus subtilis DNA polymerase IIIC using [3H]dTMP 250 pM (30 degree C for 10 min)				J Med Chem 48: 7063-74 (2005) Article DOI: 10.1021/jm050517r BindingDB Entry DOI: 10.7270/Q2W66MJN
					More data for this Ligand-Target Pair